Preventing HHV-8 transmission and Kaposi’s sarcoma (KS) risk prediction and prognostication in resource-poor countries

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Kaposis sarcoma in a Nairobi hospital.

BACKGROUND Kaposi's sarcoma (KS) is associated epidemiologically with HIV infection and a number of countries have reported a dramatic increase in the incidence of KS with the advent of AIDS. Although AIDS is prevalent in Kenya, no studies on the impact of AIDS on the pattern of KS has been carried out. OBJECTIVE To determine any changes in the pattern of KS that might have occurred since the...

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Experimental Transmission of Kaposi's Sarcoma–Associated Herpesvirus (Kshv/Hhv-8) to Scid-Hu Thy/Liv Mice

Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) is a novel human lymphotropic herpesvirus linked to several human neoplasms. To date, no animal model for infection by this virus has been described. We have examined the susceptibility of C.B-17 scid/scid mice implanted with human fetal thymus and liver grafts (SCID-hu Thy/Liv mice) to KSHV infection. KSHV virions were inoculated directly in...

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Tuberculosis in resource poor countries

Robert Colebunders head HIV/STD Unit, Clinical Sciences Department, Institute of Tropical Medicine 2000 Antwerp, Belgium bcoleb@itg.be Ludwig Apers clinician Epidemiology Unit, Public Health Department, Institute of Tropical Medicine Greet Dieltiens epidemiologist William Worodria clinician HIV/STD Unit, Clinical Sciences Department, Infectious Diseases Institute, Kampala, Uganda Competing inte...

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Kaposi sarcoma (KS)-associated herpesvirus microRNA sequence analysis and KS risk in a European AIDS-KS case control study.

BACKGROUND We recently identified polymorphisms in Kaposi sarcoma-associated herpesvirus (KSHV)-encoded microRNA (miRNA) sequences from clinical subjects. Here, we examine whether any of these may contribute to KS risk in a European AIDS-KS case-control study. METHODS KSHV load in peripheral blood was determined by real-time quantitative polymerase chain reaction. Samples that had detectable ...

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simulation and experimental studies for prediction mineral scale formation in oil field during mixing of injection and formation water

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ژورنال

عنوان ژورنال: Infectious Agents and Cancer

سال: 2010

ISSN: 1750-9378

DOI: 10.1186/1750-9378-5-s1-a66